Spouses often monitor and seek to alter each other’s health behavior, but such social control attempts can provoke behavioral resistance and emotional distress. Expectations regarding spouses’ roles in their partners’ health may influence reactions to spousal social control, with resistance and hostility less likely to occur among people who believe spouses should be involved in their partners’ health. Evidence consistent with this idea emerged in a study of 191 patients with type 2 diabetes. Patients with greater expectations for spousal involvement (particularly females) generally reacted less negatively to spousal control. The findings help to clarify when people with a chronic illness are likely to resist and resent, rather than appreciate, spousal control.