Abstract
Purpose
Cancer registry survival analyses have shown that adolescent and young adult patients with low socioeconomic status (SES)
have reduced survival compared to those with higher SES. The objective of this study was to determine whether neighborhood-
(nSES) and/or individual-level SES (iSES) also predicted current quality of life in adolescent and young adult survivors.
have reduced survival compared to those with higher SES. The objective of this study was to determine whether neighborhood-
(nSES) and/or individual-level SES (iSES) also predicted current quality of life in adolescent and young adult survivors.
Methods
The Socioeconomics and Quality of Life study surveyed adolescent and young adult survivors of leukemia and lymphoma at least
one year post-diagnosis using population-based ascertainment. Factor analysis was used to create a multidimensional age-relevant
iSES score and compared with a preexisting census-block-group derived nSES score. Four quality of life domains were assessed:
physical health, psychological and emotional well-being, social relationships, and life skills. Nested multivariable linear
regression models were run to test the associations between both SES measures and quality of life and to compare the explanatory
power of nSES and iSES.
one year post-diagnosis using population-based ascertainment. Factor analysis was used to create a multidimensional age-relevant
iSES score and compared with a preexisting census-block-group derived nSES score. Four quality of life domains were assessed:
physical health, psychological and emotional well-being, social relationships, and life skills. Nested multivariable linear
regression models were run to test the associations between both SES measures and quality of life and to compare the explanatory
power of nSES and iSES.
Results
Data from 110 individuals aged 16–40 were included in the final analysis. After adjustment for sociodemographic confounders,
low nSES was associated only with poorer physical health, whereas low iSES was related to poorer quality of life in all four
domains with iSES accounting for an additional 14, 12, 25, and 10 % of the variance, respectively.
low nSES was associated only with poorer physical health, whereas low iSES was related to poorer quality of life in all four
domains with iSES accounting for an additional 14, 12, 25, and 10 % of the variance, respectively.
- Content Type Journal Article
- Pages 1-13
- DOI 10.1007/s11136-012-0254-z
- Authors
- Erin E. Kent, Cancer Prevention Fellowship Program, National Cancer Institute, National Institutes of Health, 6116 Executive Blvd, Room 404, Bethesda, MD 20892, USA
- Leonard S. Sender, Department of Epidemiology, University of California, Irvine, Irvine, CA, USA
- Rebecca A. Morris, Hyundai Cancer Institute, CHOC Children’s Hospital, Orange, CA, USA
- Timothy J. Grigsby, Institute for Health Promotion and Disease Prevention, Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA
- Michael J. Montoya, Department of Anthropology, University of California, Irvine, Irvine, CA, USA
- Argyrios Ziogas, Department of Epidemiology, University of California, Irvine, Irvine, CA, USA
- Hoda Anton-Culver, Department of Epidemiology, University of California, Irvine, Irvine, CA, USA
- Journal Quality of Life Research
- Online ISSN 1573-2649
- Print ISSN 0962-9343