Abstract
Testis cancer-specific survival (CSS) varies by Hispanic ethnicity. Our goal was to assess whether neighborhood socioeconomic
status (SES) accounts for elevated testis CSS among Hispanic patients. We queried the Surveillance, Epidemiology, and End
Results (SEER) database for Hispanic (HW) and Non-Hispanic white (NHW) patients. Multivariate Cox regression analyses evaluated
Hispanic ethnicity’s impact on tCSS while adjusting for neighborhood socioeconomic status (education and income levels). HWs
constituted 14.3% of the 26,258 patients in the cohort. Neighborhood SES factors such as county income (P < 0.001) and education level (P < 0.001) were significant predictors of testis cancer-specific survival (tCSS). Controlling for SES and other variables,
Hispanic ethnicity remained a significant predictor of tCSS. Compared to NHWs, HWs experienced a 41% greater cancer-specific
mortality (HR: 1.406, 95% CI: 1.178–1.678, P < 0.001). The mechanism underlying the increased testis cancer mortality experienced by Hispanic patients remains unknown.
status (SES) accounts for elevated testis CSS among Hispanic patients. We queried the Surveillance, Epidemiology, and End
Results (SEER) database for Hispanic (HW) and Non-Hispanic white (NHW) patients. Multivariate Cox regression analyses evaluated
Hispanic ethnicity’s impact on tCSS while adjusting for neighborhood socioeconomic status (education and income levels). HWs
constituted 14.3% of the 26,258 patients in the cohort. Neighborhood SES factors such as county income (P < 0.001) and education level (P < 0.001) were significant predictors of testis cancer-specific survival (tCSS). Controlling for SES and other variables,
Hispanic ethnicity remained a significant predictor of tCSS. Compared to NHWs, HWs experienced a 41% greater cancer-specific
mortality (HR: 1.406, 95% CI: 1.178–1.678, P < 0.001). The mechanism underlying the increased testis cancer mortality experienced by Hispanic patients remains unknown.
- Content Type Journal Article
- DOI 10.1007/s10903-010-9419-4
- Authors
- Timothy V. Johnson, Department of Urology, Emory University, 1365 Clifton Road NE, Atlanta, GA 30322, USA
- Wayland Hsiao, Department of Urology, Weill Cornell Medical College, New York, NY USA
- Ashesh Jani, Department of Radiation Oncology, Emory University, Druid Hills, GA USA
- Viraj A. Master, Department of Urology, Emory University, 1365 Clifton Road NE, Atlanta, GA 30322, USA
- Journal Journal of Immigrant and Minority Health
- Online ISSN 1557-1920
- Print ISSN 1557-1912