The present study was designed to examine the relationship between self-stigma and quality of life over a one year time period for 71 people with mental illness who were receiving compulsory community mental health treatment. It was hypothesized that, over time, self-stigma would have the direct effect of eroding quality of life among people with mental illness who were receiving compulsory community treatment; however, this relationship was not confirmed by the data. Although the cross-sectional analyses revealed a moderate, negative relationship between self-stigma and quality of life, the longitudinal analyses indicated that self-stigma was not a significant predictor of quality of life. Among the variables measured in the current study, psychiatric symptom severity was the strongest predictor of quality of life.