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Validation of the Brazilian version of Chronic Liver Disease Questionnaire

Abstract

Purpose  

The aim of this study was to validate the Chronic Liver Disease Questionnaire (CLDQ) for use in Brazilian population.

Method  

A total of 200 patients with chronic liver disease and varying disease severity answered a socio-demographic questionnaire,
t CLDQ, and the Medical Outcome Study Short Form 36 (SF-36). Patients returned in 1–15 days to answer CLDQ again. The Cronbach’s
alpha of the total CLDQ score was 0.95 and fluctuated between 0.69 and 0.83 in its six domains.

Results  

The intra-class correlation between total CLDQ scores in two evaluations was 0.97 and in all domains was >0.93. CLDQ was moderately
correlated with the SF-36, 0.63 (total CLDQ vs. vitality, SF-36), 0.62 (CLDQ and mental health, SF-36), 0.62 (preoccupation,
CLDQ, vs. General Health, SF-36), 0.59 (fatigue, CLDQ, vs. vitality, SF-36), 0.59 (activity, CLDQ, vs. vitality, SF-36), and
0.59 (fatigue, CLDQ, vs. mental health, SF-36). The highest scores were found in non-cirrhotic group. Child A patients had
higher average scores than Child B and C groups in all domains, while patients with MELD <15 scored higher than patients with
MELD ≥15.

Conclusion  

CLDQ-BR was validated in Brazilian population and was appropriate for use in patients with liver disease of different etiologies
and degrees of severity.

  • Content Type Journal Article
  • Category Brief Communication
  • Pages 1-6
  • DOI 10.1007/s11136-012-0138-2
  • Authors
    • Samantha Mucci, Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil
    • Vanessa de Albuquerque Citero, Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil
    • Adriano Miziara Gonzalez, Department of Surgical Gastroenterology, Universidade Federal de São Paulo, São Paulo, Brazil
    • Luciana Geocze, Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil
    • Stephan Geocze, Department of Clinical Gastroenterology, Universidade Federal de São Paulo, São Paulo, Brazil
    • Gaspar de Jesus Lopes Filho, Department of Surgical Gastroenterology, Universidade Federal de São Paulo, São Paulo, Brazil
    • Mario Alfredo De Marco, Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil
    • Edison Roberto Parise, Department of Clinical Gastroenterology, Universidade Federal de São Paulo, São Paulo, Brazil
    • Luiz Antonio Nogueira Martins, Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil
    • Journal Quality of Life Research
    • Online ISSN 1573-2649
    • Print ISSN 0962-9343
Posted in: Journal Article Abstracts on 03/07/2012 | Link to this post on IFP |
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