Abstract
Percutaneous coronary revascularisation [PCR] improves angina and health related quality of life [HRQOL] compared to standard
medical therapy. It is unknown whether PCR has the same benefits for patients with a history of CABG. Over a period of 5 years,
we assessed HRQOL of patients undergoing PCR using Part 1 of the Nottingham Health Profile [NHP] at baseline 3, 12 and 24 months.
We compared HRQOL after PCR in 255 patients with CABG to 2680 without. There were more males [81.1% v 69.6% p = 0.002] and older patients [mean age 60.1 years v. 58.0 p = 0.03] in CABG group. Perceived HRQOL improved at 24 months for pain, energy and emotional reaction but the improvement
was less in the CABG group. However, mean NHP scores at 24 months for those with CABG had returned to baseline levels for
sleep [34.9] and for physical function was worse than at baseline [22.0 vs 30.7]. This relationship persisted after adjustment
for male sex, history of previous MI and coronary stent usage. Patients with previous CABG had less improvement in HRQOL after
PCR. Further work is needed to assess the benefits and cost effectiveness of PCR in these patients.
medical therapy. It is unknown whether PCR has the same benefits for patients with a history of CABG. Over a period of 5 years,
we assessed HRQOL of patients undergoing PCR using Part 1 of the Nottingham Health Profile [NHP] at baseline 3, 12 and 24 months.
We compared HRQOL after PCR in 255 patients with CABG to 2680 without. There were more males [81.1% v 69.6% p = 0.002] and older patients [mean age 60.1 years v. 58.0 p = 0.03] in CABG group. Perceived HRQOL improved at 24 months for pain, energy and emotional reaction but the improvement
was less in the CABG group. However, mean NHP scores at 24 months for those with CABG had returned to baseline levels for
sleep [34.9] and for physical function was worse than at baseline [22.0 vs 30.7]. This relationship persisted after adjustment
for male sex, history of previous MI and coronary stent usage. Patients with previous CABG had less improvement in HRQOL after
PCR. Further work is needed to assess the benefits and cost effectiveness of PCR in these patients.
- Content Type Journal Article
- DOI 10.1007/s11482-010-9130-6
- Authors
- Girish N. Viswanathan, Institute of Cellular Medicine, Newcastle University, NE7 7DN Newcastle upon Tyne, UK
- Gnanamoorthy Mayurathan, Freeman Hospital, Newcastle upon Tyne, UK
- Tony Hildreth, Research and Development, City Hospital, Sunderland, UK
- Stephen G. Worthley, Adelaide University and Royal Adelaide Hospital, Adelaide, South Australia
- Azfar G. Zaman, Institute of Cellular Medicine, Newcastle University, NE7 7DN Newcastle upon Tyne, UK
- Journal Applied Research in Quality of Life
- Online ISSN 1871-2576
- Print ISSN 1871-2584