US immigration policies have profound impacts on immigrant families. In a robust field of study across disciplines, scholars have documented how the multi-layered, complex immigration regime opens and closes doors to opportunity, health, education, safety, and peace. With a rise in harsh and unpredictable enforcement practices, immigrant families—including undocumented, liminally legal, and US citizen members—navigate the contradictory laws at the federal, state, and local levels to thrive as best as they can. In our review, we encourage scholars to extend their analysis to what happens during the migrant journey and at the border, as these experiences are also impacted by US immigration policies and potentially impact families long after they settle in the United States. The ever-changing labyrinthine legal landscape and its expansive reach provide fertile ground for further research, and we urge scholars to center ethics in their work with immigrant families made vulnerable through immigration laws.