The increase in bacterial drug resistance has become a serious public health problem worldwide. The application of antibiotics involves various clinical departments, and the rational application of antibiotics is the key to improve the efficacy. In order to provide a basis for further improving the etiological submission rate and standardizing the rational use of antibiotics, this article discussed the intervention effect of multi department cooperation on improving the etiological submission rate before antibiotic treatment.
A total of 87607 patients were involved in this study and divided into the control group (45890) and the intervention group (41717) according to whether multi-sector cooperation management was implemented. The intervention group involves the etiology examination rate before antimicrobial therapy of hospitalized patients from August to December 2021, and the control group involves it from August to December 2020. The submission rates of the two groups, and before antibiotic treatment at the unrestricted use level, the restricted use level and the special use level in departments and the timing of submission were compared and analyzed.
The overall differences in etiological submission rate before antibiotic treatment at the unrestricted use level (20.70% vs 55.98%), the restricted use level (38.23% vs 66.58%) and the special use level (84.92% vs 93.14%) were statistically significant before and after the intervention (P <0.05). At the more specific level, the etiological submission rates of different departments before antibiotic treatment at the unrestricted use level, the restricted use level and the special use level have all been improved, but the special activities of multi-sector cooperation management did not improve the submission timing significantly.
Multi-department cooperation can effectively improve the pathogen detection rate before antimicrobial treatment, but it is necessary to improve measures for specific departments to improve the long-term management and incentive and restraint mechanism.