Abstract
People occupying stigmatized social positions often withdraw from sources of social support, becoming stressed, depressed, and isolated. Homelessness is globally prevalent and stigmatized. Despite the overwhelming evidence that homelessness is associated with experiences of isolation and poor mental health, there is a sparse understanding of how stigma and social relationships interact with mental health in this context. This mixed-method study presents evidence that relationship breakdown is a common precedent to experiences of homelessness. It further shows that people withdraw from potential sources of support due to the stigma associated with homelessness. The findings demonstrate that universal forms of social contact and perceived social support do not consistently associate with mental health. Rather, distinct types of support, from different support sources, are associated with higher levels of mental health. Policy implications considering the relationship of stigma and social relationships within the context of homelessness are discussed.