This article investigates the determinants of Latino immigrants’ travel mode choices (auto alone, carpool, transit, and other modes) from six different immigrant gateways: Atlanta, Chicago, Denver, Los Angeles, Seattle, and Washington, D.C. Particular emphasis is placed on the role of living in ethnically concentrated locations and working in ethnically concentrated employment sectors in shaping their choices. The results indicate that living in areas with higher ethnic concentrations increases both the likelihood of carpooling and of taking public transit. Furthermore, working in an ethnic niche is a strong predictor of carpooling versus driving alone in five metropolitan areas, and of taking transit versus driving alone in four metropolitan areas.