The Promoting Relationships and Eliminating Violence Network (PREVNet) involves Canadian researchers and national organizations working to promote healthy relationships and prevent bullying. In this paper, we provide the rationale for establishing PREVNet, a description of the work of the network, and an assessment of the success of PREVNet. PREVNet’s strategic plan focuses on enhancing the practice of those who work with children and youth through knowledge mobilization under four strategy pillars: education and training, assessment and evaluation, prevention and intervention, and policy and advocacy. For this paper, we focus on proximal indicators of PREVNet’s success: growth of the network, participation in network activities, and development of knowledge mobilization resources. We illustrate that building partnerships with national organizations has been highly effective in the generation and dissemination of knowledge relating to children’s healthy development and healthy relationships.