Completed on September 30, 2013, the report documents the projects, programs, and initiatives of more than three dozen federal agencies, departments, and offices—one of the largest interagency collaborations in federal government history. With agencies’ commitment to implementing gender-responsive, trauma-informed approaches, this report addresses the growing national interest in this issue, the work of the Federal Partners Committee, and the specific progress that participating agencies have made over the past three years (2010-2013), since the Committee’s publication of its first report in 2011. This new report, developed with support from SAMHSA’s National Center for Trauma-Informed Care, clearly demonstrates the application of trauma-informed approaches across a wide range of settings and systems and encourages other governmental and nongovernmental agencies to implement a cross-sector, interagency, inter-systems’ realization, recognition, and response to trauma.