Drugs: True Stories is a multimedia intervention designed to prevent drug use among young people in grades 5-12 by positively changing the attitudes of youth and their parents and other caregivers in regard to the use of drugs. The intervention features a 30-minute video, which includes two vignettes of teenagers telling their personal stories to illustrate the harms associated with drug use, how teenagers and their families can work together to help teenagers abstain from drug use, possibilities for teenagers to recover from drug dependence, and how making smart choices can save lives. Program content includes the following topics: risks of drug experimentation, denial by the user and family members, addiction, recovery, and the benefits of avoiding drug use. The video is accompanied by a discussion guide, which is designed to provoke candid conversation regarding drug use and offers questions for youth, parents, and caregivers who are participating in the program. The intervention can be delivered in its entirety or in segments (e.g., three 50-minute sessions). A 1-day training on program implementation is available.