This meta-analysis synthesizes the findings of 60 independent samples from 51 studies examining racial/ethnic discrimination against Latina/os in the United States. The purpose was to identify individual-level resources and outcomes that most strongly relate to discrimination. Discrimination against Latina/os significantly results in outcomes pertaining to health, mental health, education, and employment. Mental health indicators have the strongest correlations with discrimination. Among the individual resources resulting from this meta-analysis—personal constructs and strengths, social support, acculturation, enculturation, acculturative stress, and active coping skills—personal constructs and strengths (e.g., self-esteem and self-efficacy) have the strongest correlations with discrimination and outcomes. These findings are significantly moderated by sample age, ethnicity, and regionality. Implications of these findings are discussed.