In 2004, the Office of the Assistant Deputy estimated that the total number of Veterans with dementia would be as high as 563,758 in FY 2010. Individuals with dementia are frequently cared for at home by a friend or family member. The progressive nature of the illness and the intensity of care that may be required in caring for a loved one with dementia have physical, emotional, and psychological impacts on the caregiver (CG). The purpose of this report is to review systematically the evidence on the effects of CG interventions on CG burden, mood (including depression and anxiety), and ability to manage problematic behavior, as well as the effects on the care recipient (CR).