Objectives:
The objective of this review was to determine if the occurrence of post-operative nausea and vomiting [PONV] was affected using sugammadex or neostigmine, in adult patients undergoing laparoscopic procedures paralyzed by rocuronium.
Introduction:
Laparoscopic procedures significantly increase the occurrence of PONV. Focus should be on preventing the occurrence of PONV. Laparoscopic procedures use neo-muscular blocking agents to assist with creation of a pneumoperitoneum. After the procedure is complete, reversal of these agents is critical for patient recovery. Understanding the effects for each of the reversal medications is important for future decisions for peri-operative care.
Inclusion criteria:
It will consider studies with patients aged 18 and older, undergoing laparoscopic procedures, paralyzed with Rocuronium.
Methods:
A search for relevant published and unpublished literature was conducted through February 13. Databases searched included PubMed, CINAHL, Embase and Cochrane Central Register of Controlled Trials (CENTRAL), in addition to gray literature sources. Articles that met the inclusion criteria were further assessed for methodological validity by two independent reviewers using the standard critical appraisal instruments from Joanna Briggs Institute. Data were extracted from papers included in the review using the standardized data extraction tool from the Joanna Briggs Institute. Quantitative data were pooled for statistical meta-analysis to evaluate the occurrence of PONV with both sugammadex and neostigmine.
Correspondence: Angela Jeanette Freundlich, aporc2@lsuhsc.edu
The authors declare no conflict of interest.
© 2019 by Lippincott williams & Wilkins, Inc.