With one quarter of the world’s children at risk, ensuring quality of early childhood development programs (ECD) on a global scale is more crucial than ever. A report and corresponding issue brief shed light on the importance of equity in both access and quality in these ECD programs. Based on the latest research, the authors conceptualize quality across settings and systems and identify implications for policymakers, practitioners, and researchers on how they can work together to measure, improve, and sustain quality.