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Epidemiology of external causes of morbidity and mortality in Tabriz, Iran: a multicentre hospital-based study using linked health information system and trauma registry data, 2011-2023, classified by International Classification of Diseases

Background

External causes of morbidity and mortality are leading contributors to disability and death. However, epidemiological research on the causes remains limited, mostly in low- and middle-income countries. We aimed to investigate these causes using large-scale data.

Methods

This retrospective study used International Classification-coded data from health information system and trauma registry at trauma hospitals (2011–2023). Associations were examined using generalised ordered logistic regression.

Results

Among 329 989 patients (mean age: 36.2 years), 58.94% were male. The most common single and multiple injuries were head and wrist/hand injuries, respectively. Deceased patients were younger than those discharged. Severe/fatal limb injuries were linked to shorter hospital stays. Leading causes included falls, mechanical forces, exposure to temperature/poison/nature and road traffic crashes. Females were more likely to be discharged, or survive compared with males. Adults and older adults showed worse outcomes than those ≤17 years. (severe/death, coefficient: 1.43, 95% CI 1.318 to 1.535, p<0.001). A longer stay (≥10 days) was significantly associated with worse outcomes (coefficient: 2.58, 95% CI 2.453 to 2.707, p<0.001). Road traffic crashes showed the strongest association with severe/fatal outcomes (coefficient: 2.66, 95% CI 2.546 to 2.764, p<0.001), followed by assaults, exposure to temperature/poison/nature and falls. The model demonstrated good fit (²(8)=7.85, p=0.165; pseudo R2=0.22).

Conclusions

Falls were the most frequent external cause. Road traffic crashes were most strongly linked to severe outcomes. Mechanical forces and exposure to temperature/poison/nature contributed to the injury burden. Prevention strategies should address fall prevention, residential and occupational safety and road traffic safety and public education, particularly for adult and older males.

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Posted in: Journal Article Abstracts on 06/27/2026 | Link to this post on IFP |
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