Women who report sex with women are thought to have a lower risk of Chlamydia trachomatis (CT) infection than women who report sex with men only (WSM-only), but comparisons of lifetime burden are limited.
Methods
Among 1418 sexually experienced women aged 18 to 39 years participating in the National Health and Nutrition Examination Survey (2013–2016), we estimated weighted CT seroprevalence and Wald-based 95% confidence intervals (CIs) in women who reported ever having sex with a woman (all reported having sex with men also) (WSWM) compared with WSM-only. We defined seropositivity as detection of Pgp3 antibodies and used stratified Poisson regression with robust standard errors to estimate prevalence ratios (PRs).
Results
More than half (58.3%) were White non-Hispanic; 16.2% were WSWM. Women who had sex with women and men were somewhat younger (mean, 27.8 vs. 29.0 years; P = 0.07), were younger at sexual debut (mean, 15.6 vs. 17.5 years; P