In the UK, there has been increased awareness of the harm adolescents face beyond their families. There is no national strategy for safeguarding adolescents. One intervention that comes with particularly high costs is relocation placements by children’s social care that move adolescents some distance from their communities. This research aims to contribute to the evidence about the relocation of adolescents exposed to, or at risk of extra-familial risk/harm. The research reported here sought to explore the costs associated with relocation placements. Data were gathered about the time taken to carry out the social work processes associated with relocation placements and about the costs associated with the placements. Two interviews and six focus groups were conducted with twenty-four participants. The findings highlight that each adolescent had a unique context, which was influenced by the type of extra-familial risk/harm. The service response therefore needed to be tailored, and unit costs are presented as a range from £22,000 to £170,000 for six months. There is substantial variability in the use and costs of relocation placements. The findings offer evidence for earlier intervention to avoid extra-familial risk/harm. The financial costs of relocation placements need to be considered within the context of the well-being of adolescents.