Disability inclusion has been firmly established as a human rights issue in humanitarian action. Numerous stakeholders have entered into commitments and designed policies to make their services inclusive and accessible for persons with disabilities. In practice, however, persons with disabilities are still excluded from participating in humanitarian action and cannot access the services they need. Drawing on evidence from the Rohingya refugee response in Cox’s Bazar, Bangladesh and the civil war in South Sudan, this policy and practice note shows that humanitarians often lack the knowledge and confidence to make their services inclusive for persons with different types of impairments. To anchor disability inclusion in all programmes and operations, it should be treated as a strategic issue. It requires sustainable and reliable funding, capacity development at the individual, organizational and strategic level of the humanitarian response, better coordination, robust and reliable data collection based on quantitative and qualitative assessments, and meaningful participation with organizations of persons with disabilities that represent the diversity of persons with disabilities.