This study investigated the associations of multidimensional perfectionism with positive affect and negative outcomes (affect and Obsessive–Compulsive Personality Disorder [OCPD] pathological traits) through network analysis. The sample consisted of 604 Brazilian adults aged 18–74 years. The network analysis showed that perfectionistic concerns (PC) is strongly and positively associated with negative outcomes, while perfectionistic strivings (PS) maintain positive associations with positive affect, but not negative affect. Negative affect seems to operate as a bridge between perfectionism and OCPD pathological traits, raising crucial questions about the antecedent and consequential role of affect for understanding perfectionism’s development and the traits observed in individuals with OCPD. We discuss the limitations and strengths of the study.