This study is an empirical response to the scholarly debate regarding sex work and sex worker empowerment. It drew on job satisfaction literature to derive a theoretical model of pathways for job satisfaction in sex work. It tested this model with data from 96 migrant sex workers from China. It used Qualitative Comparative Analysis (QCA) to examine the conjunctive pathways among workers who reported that they were satisfied with their vocation. Of the 96 women interviewed, 12 experienced job satisfaction. QCA identified three antecedent conditions as necessary for producing job satisfaction and two additional conditions, either one of which was also necessary. Job satisfaction required: (1) full awareness of the nature of their work prior to starting, (2) perceived agency, and (3) enjoyment of earnings, beyond meeting survival needs. It also required at least one of two additional antecedents: perceiving workplace autonomy or having a favorable workplace environment. This study demonstrates that, while genuine job satisfaction may be relatively rare for sex workers, there are pathways that make it possible.