Thousands of children die each year as a result of unintentional injuries. Some of these deaths may be preventable. Given that there are different types of safety responses, a comprehensive review of the literature would provide information on important deficits and avenues for future research. The purpose of the present review was to evaluate the extant literature on procedures for teaching safety responses and provide suggestions and considerations for future research. Our review of the literature revealed that although many safety categories are well represented in the current literature, others still warrant investigation. Furthermore, there is a call for future researchers to provide a more systematic description of experimental procedures and participants in their papers to allow for future replications. Future research would also benefit from further evaluations into specific procedural modifications that will lead to better generalization of safety responses to naturalistic settings and long-term maintenance outcomes.