Abstract
Purpose
The aims of this study are to compare self-reported sleep quality in adult survivors of childhood brain tumors and a population-based
comparison group, to identify treatment-related factors associated with sleep disturbances, and to identify the impact of
post-treatment obesity and depression on sleep scores in adult survivors of childhood brain tumors.
comparison group, to identify treatment-related factors associated with sleep disturbances, and to identify the impact of
post-treatment obesity and depression on sleep scores in adult survivors of childhood brain tumors.
Methods
Randomly selected adult survivors of childhood brain tumors (n = 78) and age-, sex-, and zip code-matched population-group members (n = 78) completed the Pittsburgh Sleep Quality Index and the Brief Symptom Inventory. Sleep quality and the effect of demographic,
treatment, and post-treatment characteristics were evaluated with linear and logistic regression analyses.
treatment, and post-treatment characteristics were evaluated with linear and logistic regression analyses.
Results
Brain tumor survivors were 2.7 (95 % CI, 1.1, 6.5) times more likely than the comparison group to take greater than 30 min
to fall asleep. Females in both groups reported worse sleep quality and impaired daytime functioning. Among survivors, post-treatment
obesity was associated with daytime dysfunction.
to fall asleep. Females in both groups reported worse sleep quality and impaired daytime functioning. Among survivors, post-treatment
obesity was associated with daytime dysfunction.
Conclusions
These results agree with previous studies associating sleep, sex, and obesity and identified longer sleep latency as being
a problem among childhood brain tumor survivors. Further study identifying factors contributing to sleep latency, and its
impact on quality of life among adult survivors of childhood brain tumors is needed.
a problem among childhood brain tumor survivors. Further study identifying factors contributing to sleep latency, and its
impact on quality of life among adult survivors of childhood brain tumors is needed.
- Content Type Journal Article
- Pages 1-9
- DOI 10.1007/s11136-012-0208-5
- Authors
- Vikki G. Nolan, Department of Epidemiology and Biostatistics, University of Memphis, School of Public Health, 3820 Desoto Avenue, Browning Hall Room 227, Memphis, TN 38152, USA
- Roxanna Gapstur, School of Nursing, University of Minnesota Medical School, Minneapolis, MN, USA
- Cynthia R. Gross, School of Nursing, University of Minnesota Medical School, Minneapolis, MN, USA
- Lauren A. DeSain, School of Public Health, University of Memphis, Memphis, TN, USA
- Joseph P. Neglia, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA
- Amar Gajjar, Departments of Oncology, St. Jude Children’s Research, Memphis, TN, USA
- James L. Klosky, Department of Psychology, St. Jude Children’s Research, Memphis, TN, USA
- Thomas E. Merchant, Department of Radiological Sciences, St. Jude Children’s Research, Memphis, TN, USA
- Marilyn Stovall, Department of Radiation Physics, MD Anderson Cancer Center, Houston, TX, USA
- Kirsten K. Ness, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, Memphis, TN, USA
- Journal Quality of Life Research
- Online ISSN 1573-2649
- Print ISSN 0962-9343