Abstract
This study was conducted to assess the association between prior history of respiratory disease and lung cancer among Mexican
Americans using data from a multi-racial/ethnic lung cancer case–control study. Cases (n = 204) were patients with previously
untreated lung cancer. Healthy control participants (n = 325) were recruited from a large physician group practice. Demographics,
cigarette use, and history of respiratory disease were collected. Multivariable logistic regression models were used to estimate
relative risk. Prior history of COPD (OR = 2.0; 95 % CI 1.2–3.3) and pneumonia (OR = 2.2; 95 % CI 1.3–3.6) were associated
with an increased risk of lung cancer. These findings illustrate that prior COPD and pneumonia are associated with an increased
risk of lung cancer among Mexican Americans. To our knowledge, this is one of largest case–control analyses assessing the
role of respiratory disease and lung cancer risk specifically among Mexican-Americans.
Americans using data from a multi-racial/ethnic lung cancer case–control study. Cases (n = 204) were patients with previously
untreated lung cancer. Healthy control participants (n = 325) were recruited from a large physician group practice. Demographics,
cigarette use, and history of respiratory disease were collected. Multivariable logistic regression models were used to estimate
relative risk. Prior history of COPD (OR = 2.0; 95 % CI 1.2–3.3) and pneumonia (OR = 2.2; 95 % CI 1.3–3.6) were associated
with an increased risk of lung cancer. These findings illustrate that prior COPD and pneumonia are associated with an increased
risk of lung cancer among Mexican Americans. To our knowledge, this is one of largest case–control analyses assessing the
role of respiratory disease and lung cancer risk specifically among Mexican-Americans.
- Content Type Journal Article
- Category Original Paper
- Pages 1-8
- DOI 10.1007/s10903-012-9690-7
- Authors
- Michelle K. McHugh, Department of Epidemiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
- Matthew B. Schabath, Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
- Chung-han Ho, Department of Epidemiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
- Mei Liu, Department of Epidemiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
- Anthony M. D’Amelio Jr., Department of Epidemiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
- Anthony J. Greisinger, Kelsey Research Foundation, Houston, TX 77005, USA
- George L. Delclos, Division of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston School of Public Health, Houston, TX 77030, USA
- Margaret R. Spitz, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
- Carol J. Etzel, Department of Epidemiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
- Journal Journal of Immigrant and Minority Health
- Online ISSN 1557-1920
- Print ISSN 1557-1912