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Evaluation of a multi-element treatment center for early psychosis in the United States

Abstract

Purpose  

A growing body of research has demonstrated the potential for comprehensive, phase-specific care to improve clinical and functional
outcomes in early psychosis. However, there have been no evaluations of such treatment models in the United States (US). This
study is a naturalistic, prospective 1-year follow-up of an early psychosis cohort treated in one of the first US-based multi-element
treatment centers.

Methods  

Participants were 163 individuals treated at the Outreach and Support Intervention Services (OASIS) clinic, a multi-element
treatment center for early psychosis. Data were collected as part of routine care at 6-month intervals. Primary outcomes included
role functioning and involvement in work or school.

Results  

Over the course of 1 year of treatment, individuals experienced significant improvements in positive and negative symptoms,
role functioning, and global functioning. The proportion of individuals meeting symptom remission and functional remission
criteria increased significantly from baseline to 1 year, as did the proportion of individuals attending school. There were
also trend-level reductions in substance abuse.

Conclusions  

This study provides preliminary support for the efficacy of comprehensive early intervention services in the US.

  • Content Type Journal Article
  • Category Original Paper
  • Pages 1-9
  • DOI 10.1007/s00127-011-0467-4
  • Authors
    • Sarah R. Uzenoff, Department of Psychology, University of North Carolina, Chapel Hill, NC, USA
    • David L. Penn, Department of Psychology, University of North Carolina, Chapel Hill, NC, USA
    • Karen A. Graham, Outreach and Support Intervention Services Program, University of North Carolina, Chapel Hill, NC, USA
    • Sylvia Saade, Outreach and Support Intervention Services Program, University of North Carolina, Chapel Hill, NC, USA
    • Barbara B. Smith, Outreach and Support Intervention Services Program, University of North Carolina, Chapel Hill, NC, USA
    • Diana O. Perkins, Outreach and Support Intervention Services Program, University of North Carolina, Chapel Hill, NC, USA
    • Journal Social Psychiatry and Psychiatric Epidemiology
    • Online ISSN 1433-9285
    • Print ISSN 0933-7954
Posted in: Journal Article Abstracts on 03/06/2012 | Link to this post on IFP |
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