Abstract
This study compared cortisol concentrations yielded using three saliva collection methods (passive drool, salivette, and sorbette)
in both in vitro and in vivo conditions, as well as method acceptability for a sample of children (n = 39) with High Functioning Autism Spectrum Disorders. No cortisol concentration differences were observed between passive
and sorbette samples obtained in vitro or in vivo. The salivette derived concentration was lower than the other two methods
for the in vitro derived comparisons but did not differ from the other methods when collected in vivo. Cross-day comparison
for the salivettes was also found to differ significantly, whereas the cross-day comparisons did not differ for the passive
method or the sorbette method. Overall, passive drool and sorbettes were found to produce similar and stable readings of cortisol,
whereas the salivette yielded unstable and variable concentrations. Ratings suggested that the children generally perceived
all methods as acceptable.
in both in vitro and in vivo conditions, as well as method acceptability for a sample of children (n = 39) with High Functioning Autism Spectrum Disorders. No cortisol concentration differences were observed between passive
and sorbette samples obtained in vitro or in vivo. The salivette derived concentration was lower than the other two methods
for the in vitro derived comparisons but did not differ from the other methods when collected in vivo. Cross-day comparison
for the salivettes was also found to differ significantly, whereas the cross-day comparisons did not differ for the passive
method or the sorbette method. Overall, passive drool and sorbettes were found to produce similar and stable readings of cortisol,
whereas the salivette yielded unstable and variable concentrations. Ratings suggested that the children generally perceived
all methods as acceptable.
- Content Type Journal Article
- Category Original Article
- Pages 1-14
- DOI 10.1007/s10578-012-0284-3
- Authors
- Susan K. Putnam, Institute for Autism Research, Canisius College, HS—210, 2001 Main Street, Buffalo, NY 14208, USA
- Christopher Lopata, Institute for Autism Research, Canisius College, HS—210, 2001 Main Street, Buffalo, NY 14208, USA
- Jeffery D. Fox, Autistic Services Inc., Williamsville, NY, USA
- Marcus L. Thomeer, Institute for Autism Research, Canisius College, HS—210, 2001 Main Street, Buffalo, NY 14208, USA
- Jonathan D. Rodgers, University at Buffalo, State University of New York, Buffalo, NY, USA
- Martin A. Volker, University at Buffalo, State University of New York, Buffalo, NY, USA
- Gloria K. Lee, University at Buffalo, State University of New York, Buffalo, NY, USA
- Erik G. Neilans, University at Buffalo, State University of New York, Buffalo, NY, USA
- Jilynn Werth, Canisius College, Buffalo, NY, USA
- Journal Child Psychiatry & Human Development
- Online ISSN 1573-3327
- Print ISSN 0009-398X