Abstract
American Indian and Alaska Native (AI/AN) populations bear a heavy burden of cardiovascular disease (CVD), and they have the
highest rates of risk factors for CVD, such as cigarette smoking, obesity, and diabetes, of any U.S. population group. Yet,
few randomized controlled trials have been launched to test potential preventive interventions in Indian Country. Five randomized
controlled trials were initiated recently in AI/AN communities to test the effectiveness of interventions targeting adults
and/or children to promote healthy behaviors that are known to impact biological CVD risk factors. This article provides a
context for and an overview of these five trials. The high burden of CVD among AI/AN populations will worsen unless behaviors
and lifestyles affecting CVD risk can be modified. These five trials, if successful, represent a starting point in addressing
these significant health disparities.
highest rates of risk factors for CVD, such as cigarette smoking, obesity, and diabetes, of any U.S. population group. Yet,
few randomized controlled trials have been launched to test potential preventive interventions in Indian Country. Five randomized
controlled trials were initiated recently in AI/AN communities to test the effectiveness of interventions targeting adults
and/or children to promote healthy behaviors that are known to impact biological CVD risk factors. This article provides a
context for and an overview of these five trials. The high burden of CVD among AI/AN populations will worsen unless behaviors
and lifestyles affecting CVD risk can be modified. These five trials, if successful, represent a starting point in addressing
these significant health disparities.
- Content Type Journal Article
- Category Literature Review
- Pages 1-7
- DOI 10.1007/s10935-012-0277-9
- Authors
- Jared B. Jobe, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, Bethesda, MD, USA
- Alexandra K. Adams, Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
- Jeffrey A. Henderson, Black Hills Center for American Indian Health, Rapid City, SD, USA
- Njeri Karanja, Center for Health Research, Kaiser Permanente, Northwest/Hawaii/Southeast, Portland, OR, USA
- Elisa T. Lee, Center for American Indian Health Research, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
- Karina L. Walters, University of Washington Indigenous Wellness Research Institute and School of Social Work, Seattle, WA, USA
- Journal The Journal of Primary Prevention
- Online ISSN 1573-6547
- Print ISSN 0278-095X