Validation of the Dutch version of the VascuQol questionnaire and the Amsterdam linear disability score in patients with intermittent claudication

To assess the reliability and validity of the Dutch version of the vascular quality of life questionnaire (VascuQol) and the
AMC Linear Disability Score (ALDS) in patients with stable intermittent claudication (IC).

During a 5-month period we performed a prospective study in which we included every patient with stable IC, who visited our
vascular surgery outpatient clinic and consented to participate. Forty consecutive patients filled in the Dutch VascuQol,
the ALDS, and Short Form-36 (SF-36). Twenty patients filled in the same questionnaires after 4 weeks. Internal reliability
consistencies were expressed as Cronbach’s α. Test–retest reliability was expressed as intraclass correlation coefficients
(ICC). Construct validity was expressed as Spearman rho correlations between SF-36 and relevant domains of Dutch VascuQol
and the ALDS.

Internal reliability consistencies were, respectively, good and excellent for the total scores of VascuQol, SF-36, and ALDS
(Cronbach’s α. 0.87, 0.89, and 0.92). Test–retest reliability was excellent for the total VascuQol scores [ICC 0.91 (95% CI,
0.78–0.96)], and for the ALDS [ICC 0.90 (95% CI, 0.76–0.96)]. Spearman correlations between VascuQol, ALDS, and SF-36 domains
varied from r = 0.34–0.79.

The Dutch VascuQol is a valid and reliable questionnaire for assessment of Qol in patients with IC. This study confirms the
good clinimetric properties of the ALDS for assessing disability in patients with IC.