Abstract
Purpose
The Functional Assessment of Cancer Therapy-Esophageal (FACT-E) Scale version 4 has been used to assess quality of life in
patients with squamous cell carcinoma undergoing chemoradiation. We sought to determine whether this scale can be used to
assess quality of life in Korean patients with esophageal cancer undergoing chemoradiation.
patients with squamous cell carcinoma undergoing chemoradiation. We sought to determine whether this scale can be used to
assess quality of life in Korean patients with esophageal cancer undergoing chemoradiation.
Methods
The FACT-E scale version 4 was cross-culturally translated into Korean. Its reliability and validity were assessed in a group
of 146 esophageal cancer patients who were scheduled for neoadjuvant chemoradiation (CRT). This procedure was followed by
esophagectomy that took place between 2007 and 2010 at Asan Medical Center. All patients completed the FACT-E, Hospital Anxiety
and Depression Scale (HADS) and Functional Living Index-Cancer (FLIC) questionnaires at baseline (pre-treatment) and 1 month
after two cycles of induction chemotherapy followed by CRT.
of 146 esophageal cancer patients who were scheduled for neoadjuvant chemoradiation (CRT). This procedure was followed by
esophagectomy that took place between 2007 and 2010 at Asan Medical Center. All patients completed the FACT-E, Hospital Anxiety
and Depression Scale (HADS) and Functional Living Index-Cancer (FLIC) questionnaires at baseline (pre-treatment) and 1 month
after two cycles of induction chemotherapy followed by CRT.
Results
In validating the FACT-E, we found high internal consistency coefficients ranging from 0.72 to 0.91. Good convergent and divergent
validities were demonstrated by the FLIC and HADS scales. The FACT-E showed good clinical validity and effectively differentiated
between patient groups with different performance status ratings and stages. Changes in clinical status were reflected by
changes in FACT-E scores, demonstrating responsiveness to neoadjuvant CRT.
validities were demonstrated by the FLIC and HADS scales. The FACT-E showed good clinical validity and effectively differentiated
between patient groups with different performance status ratings and stages. Changes in clinical status were reflected by
changes in FACT-E scores, demonstrating responsiveness to neoadjuvant CRT.
- Content Type Journal Article
- Category Brief Communication
- Pages 1-7
- DOI 10.1007/s11136-011-0050-1
- Authors
- Hee-Jung Yoo, Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Sung-Bae Kim, Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Dok Hyun Yoon, Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Seung-Il Park, Department of Thoracic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Jong-Hoon Kim, Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- David Cella, Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
- Hwoon-Yong Jung, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Gin-Hyug Lee, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Kee Don Choi, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Ho June Song, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Ho Young Song, Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Ji Hoon Shin, Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Kyung-Ja Cho, Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Journal Quality of Life Research
- Online ISSN 1573-2649
- Print ISSN 0962-9343