Mixed methods research has made significant inroads in the effort to examine complex health-related phenomena. However, little has been published on the funding of mixed methods research projects. This article addresses that gap by presenting an example of a National Institute of Mental Health–funded project using a mixed methods qualitative–quantitative triangulation design titled “The Mixed-Method Analysis of Japanese Depression.” The authors present the Cultural Determinants of Health Seeking model that framed the study, the specific aims, the quantitative and qualitative data sources informing the study, and overview of the mixing of the two methods. Finally, the authors examine reviewers’ comments and the authors’ insights related to writing mixed methods proposals for successfully achieving RO1-level funding.