This study explored what relational aspects contribute to spouses managing private, infertility-related information differently. We examined associations among relational uncertainty and partner interference and three manifestations of boundary turbulence: discrepancies in disclosures, relative discomfort, and perceived spousal acceptability. Using data from 50 infertile couples reporting on 250 social network relationships, we used multi-level modeling to test our predictions that relational uncertainty and partner interference would positively correlate with boundary turbulence. Results were partially consistent with the predictions for relational uncertainty and inconsistent with regard to partner interference partner interference. These findings suggest that relational features of a partnership coincide with a couple’s ability to coordinate boundaries about their private information and merits further research on the dyadic component of boundary coordination.