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Predictors of quality of life in type 2 diabetes patients with schizophrenia, major mood disorder, and without mental illness

Abstract

Purpose  

The aim of the current study is to compare the predictors of health-related quality of life in individuals with schizophrenia,
major mood disorder, and no mental illness, all with type 2 diabetes.

Methods  

A total of 100 individuals with schizophrenia, 101 with a major mood disorder, and 99 without mental illness, all with type
2 diabetes, rated their health-related quality of life on the Medical Outcomes Survey, Short Form-12; physical and mental
composite scores (PCS and MCS) were calculated. We performed a hierarchical multiple regression on PCS and MCS in each sample
starting with a basic set of predictors and then adding diabetes-related variables. We compared the regression weights and
incremental variance explained within each group.

Results  

The number of co-occurring medical conditions was significantly associated with lower PCS in all three groups and with lower
MCS in the no mental illness group. Diabetes-related variables added significant incremental variance to the prediction of
PCS in the no mental illness group but not in either psychiatric group.

Conclusions  

For persons with diabetes and mental illness, as well as with no mental illness, additional medical conditions exert a strong
effect on physical well-being. The impact on quality of life of diabetes-related factors may be lower in persons with diabetes
and serious mental illness compared to those with diabetes and no mental illness.

  • Content Type Journal Article
  • Pages 1-7
  • DOI 10.1007/s11136-011-9888-5
  • Authors
    • Faith Dickerson, Sheppard Pratt Health System, 6501 North Charles St., Baltimore, MD 21204, USA
    • Karen Wohlheiter, Department of Psychology, University of Maryland Baltimore County, Baltimore, MD USA
    • Deborah Medoff, Department of Psychiatry, VA Capitol Health Care Network MIRECC, University of Maryland School of Medicine, Baltimore, MD USA
    • Lijuan Fang, Department of Psychiatry, VA Capitol Health Care Network MIRECC, University of Maryland School of Medicine, Baltimore, MD USA
    • Julie Kreyenbuhl, Department of Psychiatry, VA Capitol Health Care Network MIRECC, University of Maryland School of Medicine, Baltimore, MD USA
    • Richard Goldberg, Department of Psychiatry, VA Capitol Health Care Network MIRECC, University of Maryland School of Medicine, Baltimore, MD USA
    • Clayton Brown, Department of Psychiatry, VA Capitol Health Care Network MIRECC, University of Maryland School of Medicine, Baltimore, MD USA
    • Lisa Dixon, Department of Psychiatry, VA Capitol Health Care Network MIRECC, University of Maryland School of Medicine, Baltimore, MD USA