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Measuring fatigue in persons with multiple sclerosis: creating a crosswalk between the Modified Fatigue Impact Scale and the PROMIS Fatigue Short Form

Abstract

Purpose  

To create cross-walk tables to associate scores for the Modified Fatigue Impact Scale (MFIS) with scores for the Patient Reported
Outcome Measurement Information System (PROMIS) Fatigue Short Form (SF) in persons with Multiple Sclerosis (MS).

Methods  

Cross-walk tables were created using equipercentile linking and based on data collected at one time point in a longitudinal
study of persons with MS (N = 458). Validation of the tables was conducted using data collected at a subsequent time point (N = 444). Deviations between estimates and actual scores were compared across levels of fatigue. The impact of sample size
on the precision of sample mean estimates was evaluated using bootstrapping.

Results  

Correlations between deviations and fatigue level for the PROMIS Fatigue SF and MFIS were (−0.31) and (−0.30), respectively,
indicating moderately greater deviations with lower fatigue scores. Estimated sample means were impacted by sample size.

Conclusions  

Cross-walk tables allow data from studies using different measures of fatigue to be combined to achieve larger sample sizes
and to compare results. These tables are valid for group-level analyses with sample sizes of 150 or greater.

  • Content Type Journal Article
  • Pages 1-11
  • DOI 10.1007/s11136-011-0040-3
  • Authors
    • Vanessa K. Noonan, Department of Rehabilitation Medicine, University of Washington, Box 356490, Seattle, WA 98195, USA
    • Karon F. Cook, Department of Rehabilitation Medicine, University of Washington, Box 356490, Seattle, WA 98195, USA
    • Alyssa M. Bamer, Department of Rehabilitation Medicine, University of Washington, Box 356490, Seattle, WA 98195, USA
    • Seung W. Choi, Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    • Jiseon Kim, Department of Rehabilitation Medicine, University of Washington, Box 356490, Seattle, WA 98195, USA
    • Dagmar Amtmann, Department of Rehabilitation Medicine, University of Washington, Box 356490, Seattle, WA 98195, USA