This article introduces a Special Section of the Psychology of Addictive Behaviors on “Implementing Evidence-based Interventions for Substance Use Disorders.” It briefly describes the content of each of the seven manuscripts comprising the Special Section. The articles provide a overview of conceptual frameworks for, and summarize research on, the implementation of evidence-based treatments and practices for substance use disorders. Taken together, the articles make clear that successful implementation of a treatment innovation generally requires a multifaceted approach that considers: (a) features of the clinical intervention to be implemented, (b) characteristics of the individuals that are expected to adopt the clinical intervention, (c) features of the proximal and more distal environments in which the clinical intervention will be implemented, and (d) the implementation strategy to be applied. (PsycINFO Database Record (c) 2011 APA, all rights reserved)