This study investigated whether the associations between (a) the quality of the parent-child relationship and peer acceptance and (b) early adolescents’ life satisfaction differed depending on the importance of family values in the respective culture. As part of the Value of Children Study, data from a sub-sample of N = 1,034 adolescents (58% female, M age = 13.62 years, SD = 0.60 years) from 11 cultures was analyzed. Multilevel analyses revealed a positive relation between parental admiration and adolescents’ life satisfaction independent of cultural membership. Further, the higher the importance of family values in a culture, the weaker was the positive effect of peer acceptance on adolescents’ life satisfaction. The results highlight the universal importance of parental warmth and support in adolescence and underline the effect of culturally shared family values on the role of peer acceptance for adolescent development.