There are a number of reasons why this summer’s COVID wave has been surprisingly strong. One is the emergence of successive hyperinfectious coronavirus subvariants. In the spring, some of the subvariants collectively nicknamed FLiRT, including KP.2, began a midyear wave. That was followed by ever-more-contagious successor subvariants — KP.3 (nicknamed FLuQE, pronounced “fluke”) — and the latest, KP.3.1.1 (nicknamed deFLuQE).