Tianeptine, which is approved in some countries as a prescription drug for the treatment of depression, can mimic the actions of opioids like fentanyl. As a result, it carries similar risks of addiction, withdrawal and overdose potential. It can also lead to psychosis, seizures, kidney damage and death. The FDA has been actively urging U.S. consumers to avoid the drug since 2022. But vendors continue to promote the drug as a dietary supplement, despite the fact that the FDA has explicitly stated that tianeptine “does not meet the statutory definition of a dietary ingredient and is an unsafe food additive.”