Place-based education and community change interventions such as Promise Neighborhoods face distinct challenges designing and executing high-quality evaluations. Because these efforts attempt to create population-level change by using a comprehensive continuum of cradle-to-career programming, experimental evaluation methods may be impractical or inappropriate. Nevertheless, planning, formative, and quasi-experimental methods can be used to conduct rigorous and instructive evaluations of Promise Neighborhoods. In this brief, we present options and discuss best practices for Promise Neighborhoods conducting evaluations within their communities.