This article reports the findings from a systematic review and meta-analysis of the effects of school dropout prevention programs for pregnant and parenting teens. The meta-analysis synthesized 119 effect sizes from 15 different studies measuring differences in school enrollment and completion outcomes for pregnant and parenting adolescents participating in dropout prevention programs relative to a comparison group. The study used random-effects, inverse-variance-weighted meta-analyses with robust variance estimates to synthesize odds ratios for school dropout outcomes. It used mixed-effects meta-regression models to examine the effects of program, methodological, and participant characteristics on program effects.