Abstract
Advanced prostate cancer (APC) is associated with disruptions that compromise health related quality of life (HRQOL). Treatment
often includes androgendeprivation therapy (ADT), which results in a range of side effects (e.g., fatigue, urinary dysfunction)
that further impact HRQOL. Despite these challenges, there are limited evaluations of the impact of stress and stress management
skills on HRQOL among APC survivors on ADT. This study evaluated relationships among stress, stress management skills, and
HRQOL, and it was hypothesized that better stress management skills would relate to greater physical and emotional well-being
by mitigating perceived stress levels. Participants (N = 77) were 69.7 years old (SD = 9.8), 18.6 months post-treatment (SD = 17.5), and ethnically diverse (65 % Non-Hispanic White,
13 % Hispanic, 21 % African-American). Measures included the Measure of Current Status for stress management skills, the Perceived
Stress Scale for perceived stress, and the Medical Outcomes Study—Short Form (MOS SF-36; physical functioning and emotional
well-being subscales) for HRQOL. Direct effects and mediation models were evaluated to determine the relationships between
perceived stress, stress management skills, and HRQOL domains, controlling for relevant covariates. Stress management skills
and perceived stress were significantly associated with physical functioning (β = .24, p < .05 and β = −.43, p < .01, respectively) and emotional well-being (β = .35, p < .01 and β = −.64, p < .01, respectively). Regression analyses supported the hypothesis that reduced perceived stress mediated the relationship
between stress management skills and both physical functioning and emotional well-being. These results demonstrate that one
way stress management skills may impact HRQOL is by lessening ongoing perceptions of stress.
often includes androgendeprivation therapy (ADT), which results in a range of side effects (e.g., fatigue, urinary dysfunction)
that further impact HRQOL. Despite these challenges, there are limited evaluations of the impact of stress and stress management
skills on HRQOL among APC survivors on ADT. This study evaluated relationships among stress, stress management skills, and
HRQOL, and it was hypothesized that better stress management skills would relate to greater physical and emotional well-being
by mitigating perceived stress levels. Participants (N = 77) were 69.7 years old (SD = 9.8), 18.6 months post-treatment (SD = 17.5), and ethnically diverse (65 % Non-Hispanic White,
13 % Hispanic, 21 % African-American). Measures included the Measure of Current Status for stress management skills, the Perceived
Stress Scale for perceived stress, and the Medical Outcomes Study—Short Form (MOS SF-36; physical functioning and emotional
well-being subscales) for HRQOL. Direct effects and mediation models were evaluated to determine the relationships between
perceived stress, stress management skills, and HRQOL domains, controlling for relevant covariates. Stress management skills
and perceived stress were significantly associated with physical functioning (β = .24, p < .05 and β = −.43, p < .01, respectively) and emotional well-being (β = .35, p < .01 and β = −.64, p < .01, respectively). Regression analyses supported the hypothesis that reduced perceived stress mediated the relationship
between stress management skills and both physical functioning and emotional well-being. These results demonstrate that one
way stress management skills may impact HRQOL is by lessening ongoing perceptions of stress.
- Content Type Journal Article
- Pages 1-8
- DOI 10.1007/s10880-012-9308-1
- Authors
- Frank J. Penedo, Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
- Catherine Benedict, Department of Psychology, University of Miami, P.O. Box 248185, Coral Gables, FL 33124-0751, USA
- Eric S. Zhou, Department of Psychology, University of Miami, P.O. Box 248185, Coral Gables, FL 33124-0751, USA
- Mikal Rasheed, Department of Psychology, University of Miami, P.O. Box 248185, Coral Gables, FL 33124-0751, USA
- Lara Traeger, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
- Bruce R. Kava, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA
- Mark Soloway, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA
- Sara Czaja, Department of Psychiatry and Behavioral Sciences, University of Miami, Miami, FL, USA
- Michael H. Antoni, Department of Psychology, University of Miami, P.O. Box 248185, Coral Gables, FL 33124-0751, USA
- Journal Journal of Clinical Psychology in Medical Settings
- Online ISSN 1573-3572
- Print ISSN 1068-9583