This exploratory qualitative study examines the healthcare experiences of sixteen Anicinapek men from the communities of Lac Simon and Kitcisakik in north-western Quebec, Canada, focusing on their perspectives regarding Indigenous and non-Indigenous medicine. Participants expressed strong support for Indigenous medicine, valuing its role in long-term healing, its deep spiritual connection, and its grounding in ancestral knowledge and cultural identity. While some voiced concerns about biomedical care, most acknowledged its importance, particularly for the treatment of chronic conditions. The findings highlight the need for social workers and healthcare professionals to adopt culturally responsive approaches that integrate traditional healing practices within contemporary care models. Recognizing the Indigenous wellness wheel, which encompasses physical, mental, emotional, and spiritual dimensions, as a guiding framework is essential. Such practice also requires an understanding of the ongoing impacts of colonization and intergenerational trauma, as well as the central role Indigenous medicine plays in community resilience and self-determination.