Farmer cooperatives are community-based organizations that drive local farming by facilitating knowledge sharing and building skills for rural community food security. They are essential groups for meeting immediate needs and tackling the root causes of food shortages. Yet, donor-driven, rather than community-anchored, agricultural interventions, inherently established to drive support to farmer cooperatives, can hinder their potential to support and perpetuate food insecurity depending on the implementation strategy. This study examined cooperative farmers’ knowledge, attitudes, and practices (KAP) regarding agricultural interventions in Rwanda’s rural District, Rutsiro, in the Western Province. We used KAP and social cognitive theory to guide our analysis. We conducted six focus group discussions and three key informant interviews and analyzed the data using a thematic approach. Results indicate four major findings: (1) Farmers are aware of some interventions but lack knowledge of others; (2) Knowledge gaps and resistance to change strongly shape attitudes and practices; (3) Poor diets and hygiene worsen household food insecurity; and (4) The level of knowledge, attitudes, and practices among smallholder cooperative farmers relies heavily on the approaches of the interventions. We recommend forming multidisciplinary teams, including social workers, to actively strengthen farmers’ KAP on agricultural interventions.