While it is possible that some individuals may take ketamine and use its consciousness-altering experience as a springboard to make beneficial life changes, many others, seeking a repeat pleasurable ketamine state, will simply become regular clinic customers. Most of them will not, as was the case with Matthew Perry, proceed from legal clinics to purchasing ketamine illegally and die from it. However, if they believe that ketamine can “create healthy circuits” and “regrow synapses,” they may see their relapses as indicating a need for more ketamine, rather than recognizing that a long-term antidote to depression requires difficult life changes. Above: Ketamine solution poured onto glass and left to dry.