Liver transplantation requires lifelong immunosuppression, which has significant psychological and physiological implications. While depression and anxiety are prevalent among transplant recipients, their potential relationship with immune tolerance remains unclear. This study aims to evaluate the association between depression, anxiety, and immune tolerance in liver transplant (LT) recipients.
Methods:
This cross-sectional study included 179 adult LT recipients, categorized as tolerant (n=49) and nontolerant (n=130) based on immunosuppressive status. Depression and anxiety levels were assessed using the Beck Depression Inventory-II and Spielberger’s State-Trait Anxiety Inventory. Data were analyzed using appropriate statistical tests, with significance set at p<.05. results: a history of psychiatric disorders including depression and anxiety was observed in participants respectively. no significant differences were found beck inventory-ii scores between tolerant nontolerant groups. similarly state-trait inventory state trait did not differ significantly groups for both conclusions: while are common lt recipients this study find association with immune tolerance. given the cross-sectional design sample size limitations further longitudinal research is needed to determine whether psychological factors influence transplant outcomes. abbreviations: bdi-iibeck package social sciences>