Abstract
Parkinson’s disease is a multifaceted neurodegenerative disease that impacts quality of life (QOL) and manifests in a several of motor and non-motor symptoms. Depression is the predominate symptom, leading to a significant decline in quality of life. This study aimed to investigate the relationship between depression and quality of life (QOL) in individuals diagnosed with Parkinson’s disorder. This cross-sectional study analysed among one hundred Parkinson’s disease patients in Chennai, South India, who received treatment at movement rehabilitation centres. The participants were selected using convenience sampling, and depression was assessed using Beck’s Depression Inventory and quality of life using the Parkinson’s Disease Questionnaire 39. The results found that, 45% had extreme depression, 33% severe depression, and nearly 60% of the participants experienced a severe impact, 24% felt a moderate impact on the QOL. Depression was positively associated with quality of life (QOL), especially emotional well-being and stigma. Depression increased with lower emotional well-being and higher bodily discomfort. Linear regression predicted poorer emotional well-being and higher bodily discomfort were significant predictors of depression. Our study showed the depression has a detrimental effect on the quality of life (QOL) of Parkinson’s patients.