Nucleus of fairness: epigenetic ageing, social determinants of health and the imperative for proactive preventive measures

The study conducted by Clair et al1 reported in this issue of JECH delves into the intricate relationship between housing circumstances and epigenetic ageing, offering valuable insights into the complex interplay between genetics, environment and health outcomes through the novel perspective offered by DNA methylation data. The study ventures into relatively uncharted territory, seeking to illuminate how the place we call home might influence the fundamental biological processes underlying ageing. Their analysis hinges on the concept of epigenetic ageing, a burgeoning field of research that examines how external factors can imprint themselves on our DNA, potentially accelerating or decelerating the biological clock.

Clair et al tentatively suggest that living in privately rented homes might be linked to an accelerated biological ageing process. This assertion, however, is made cautiously, acknowledging the need for further investigation to establish a definitive causal link. Interestingly, this potential impact of housing circumstances on ageing…

Read the full article ›