The term soul is used in the traditional literature as a synonym for one’s true Self and is associated with the subjective essence of one’s living. Since, we don’t have any means to quantify it, the science has ruled out this idea from its investigations. But, in a recent study, Ceylan et al. (2017) has reintroduced the word soul to scientific literature and examined the possibility of the study of the soul through scientific modalities. The primary focus of their study is to find and understand the scientific analog of the soul as quoted and discussed in the traditional literature. In the present paper, we examine the idea of a soul that uses a novel approach; integrating neuroscience and quantum physics, as proposed in Ceylan et al. (2017). For this purpose, we make use of findings from neuroscientific studies on meditation to understand the concepts of soul and consciousness in terms of inhibition mechanisms. In this context, this paper serves as an attempt to call for more studies to discuss and expand the hypothesis about the soul as uninhibited mental activity.