Poly-victimization can occur during childhood resulting in adverse events on health and well–being. The aim of this study is to determine the prevalence of past year as well as lifetime prevalence of poly-victimization among adolescents in Saudi Arabia (SA). A cross-sectional study was conducted in the five main provinces of SA. Boys and girls (n = 16,010) from public and private secondary high schools were selected to participate in the study. Nearly three-quarters (72%) experienced poly-victimizations during their lives and two third (66%) during the past year. Participants living with extended family, and living with a biologic and step-parent were 1.3 and 1.9 times respectively more likely to be poly-victimized during their lives and were 1.2 and 1.7 times respectively during the past year. Public policy should be established that encourages social workers and child protection services to screen for poly-victimization in cases of suspected adolescent maltreatment.